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Embolization Systems
AZUR Detachable Peripheral Hydrocoil
Detachable 35 Detachable 18 Framing Coil AZUR Pushable Peripheral Hydrocoil
Pushable 35 Pushable 18


Portfolio Solutions


PAD Solutions
Embolization Solutions
Transradial Solutions

The Technology of Expansion

The AZUR Peripheral HydroCoil Embolization System combines a platinum coil and an expandable hydrogel polymer. In concert, these elements provide a uniquely stable and permanent platform for blood stasis, thrombus organization, and neointima formation.

AZUR’s hydrogel coating undergoes limited expansion within the first 3 minutes, and fully expands within 20 minutes. The result is greater filling and mechanical stability with fewer coils – nearly 5 times more filling volume for the 0.018" coil and 4 times more filling volume for the 0.035" coil (versus platinum coils of the same size). In other words, AZUR works harder so you don’t have to.

  • Superior volume filling, packing density, and occlusion efficacy 1,2
  • Superior mechanical stability 3,8,9,10
  • Permanent mechanical occlusion without the need to wait for thrombus formation
  • Increased delivery control
  • Increased long-term durability 3,8
  • Enhanced reconstruction of the artery wall (versus platinum coils) 4,9,10

Detachable or Pushable

Two distinct options.
Same expanding technology.

The AZUR detachable system is the first product in the industry to offer detachment in less than a second at the push of a button. An LED confirms that the detachment mechanism has been activated.

Using the AZUR Detachment Controller, you detach the coil only when it is properly in place. By empowering you to retract and reposition the coil until you are thoroughly satisfied with the placement, the detachable system minimizes the risk of coil migration.

Ideal for high-flow areas and challenging anatomies, the AZUR detachable system provides a whole new level of control and durability. 11,13

The AZUR pushable system works like traditional pushable coils with the added advantage of greater filling volume.

Whichever option you choose, you’ll benefit from AZUR’s unique hydrogel polymer technology. Once the coil is in place, AZUR’s hydrogel safely expands in the direction(s) of least resistance – reducing leaks and maximizing mechanical occlusion, while decreasing the number of coils required. 3,8-13

References:
1. Sluzewski M, van Rooij WJ, Slob MJ, Bescós JO, Slump CH, Wijnalda D. Relation between aneurysm volume, packing, and compaction in 145 cerebral aneurysms treated with coils. Radiology. 2004;231(3):653-658.
2. Cloft HJ, Kallmes DF. Aneurysm packing with HydroCoil Embolic System versus platinum coils: initial clinical experience. AJNR Am J Neuroradiol. 2004;25(1):60-62.
3. DURABLE Multi-center HES Registry (Albany Medical Center, Beaumont Regional Medical Center, Loyola University Medical Center) of 260 aneurysms with 186 follow-ups treated with HydroCoil. Presented at ABC/WIN. 2006.
4. Plenk H, Killer M, Richling B. Pathophysiologic considerations on HydroCoil- and platinum coil-occluded retrieved human cerebral aneurysms. Presented at ASITN MicroVention Symposium. 2005.
5. Fujiwara NH, Kallmes DF. Healing response in elastase-induced rabbit aneurysms after embolization with a new platinum coil system. AJNR Am J Neuroradiol. 2002;23(7):1137-1144.
6. Kallmes DF, Fujiwara NH. New expandable hydrogel-platinum coil hybrid device for aneurysm embolization. AJNR Am J Neuroradiol. 2002;23(9):1580-1588.
7. Bavinzski G, Talazoglu V, Killer M, et al. Gross and microscopic histopathological findings in aneurysms of the human brain treated with Guglielmi detachable coils. J Neurosurg. 1999;91(2):284-293.
8. HEAL Registry. MicroVention, Inc. (197 aneurysms; 128 follow-up cases; mean follow-up of 14 months).
9. Virmani R. Healing and inflammation in experimental and clinical aneurysms. Presented at WFITN. 2005.
10. Ding YH, Dai D, Lewis DA, Cloft HJ, Kallmes DF. Angiographic and histologic analysis of experimental aneurysms embolized with platinum coils, Matrix, and HydroCoil. AJNR Am J Neuroradiol. 2005;26(7):1757-1763.
11. Bui JT, West DL, Pai R, Owens CA. Use of a hydrogel-coated self-expandable coil to salvage a failed transcatheter embolization of a mesenteric hemorrhage. Cardiovasc Intervent Radiol. 2006;29(6):1121-1124.
12. Aina R, Oliva VL, Therasse E, et al. Arterial embolotherapy for upper gastrointestinal hemorrhage: outcome assessment. J Vasc Interv Radiol. 2001;12(2):195-200.
13. Fanning NF, Berentai Z, Brennan PR, Thornton J. HydroCoil as an adjuvant to bare platinum coil treatment of 100 cerebral aneurysms. Neuroradiology. 2007;49(2):139-148. Epub 2006 Nov 22.

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